Croup

Definition

Also called laryngotracheobronchitis, it is caused by an overactive immune response to the virus causing inflammation of the upper airways.

Etiology
  • Usually in children between 6 months and 3 years of age
  • Commonly due to parainfluenza virus infection
Clinical Features
  • Prodromal phase
    • 1-2 days
    • Rhinitis, nasal congestion, low-grade fever ± red pharynx
  • Inflammatory phase
    • 2-7 days
    • Barking cough, inspiratory stridor, widespread wheeze ± increase work of breathing ± fever
  • Mild cases:
    • Normal behaviour, normal RR, no O2 requirement, no/minimal accessory muscle use
    • Barking cough ± stridor only when active or upset
  • Moderate cases:
    • Some irritability, moderate work of breathing, increase respiratory rate, no O2 required
    • Barking cough + intermittent stridor at rest
  • Severe cases:
    • Irritable, lethargic, marked increase work of breathing, tachypnoea or bradypnoea (pre-terminal)
    • Persistent stridor at rest, hypoxemia a late sign indicating significant obstruction (life-threatening)
Investigations
  • Usually a clinical diagnosis (no routine investigations)
  • May consider CXR, FBE & culture to rule out DDx
Management
  • Minimal handling
  • Mild-moderate cases: Dexamethasone 0.15mg/kg OR Prednisolone 1mg/kg PO
  • Severe cases: nebulised adrenaline 0.5ml/kg 1:1000 (max 5ml) + IV/IM/PO dexamethasone 0.6mg/kg
  • Life-threatening: nebulised adrenaline 5ml of 1:1000, oxygen 15L/min, systemic corticosteroid
  • Discharge once stridor free at rest