Bronchiolitis In Children

Definition

Bronchiolitis is a lower respiratory tract infection that causes inflammation of the bronchioles.

Etiology
  • Caused by viral infection especially RSV, less commonly parainfluenza, adenovirus, rhinovirus, human metapneumovirus (hMPV)
  • Typically affects children under 12 months (peak age: 6 weeks – 3 months)
  • More common in winter
  • Risk factors for severe disease:
    • Prematurity
    • Male
    • Congenital heart or lung disease
    • Neurological disease
    • Immunodeficiency
    • Age <10 weeks
    • Australian Institute of Aboriginal and Torres Strait Islander background
    • Maternal smoking
Clinical Features
  • Typically begins with symptoms of acute upper respiratory tract infection: cough, rhinorrhoea
  • Followed by the onset of respiratory distress with fever ± tachypnoea, wheeze, widespread crackles, increase work of breathing
  • Peak severity usually ~day 2-3 with resolution over 7-10 days, may have a persistent cough

 

  • Mild cases:
    • Behaviour: normal interaction and feeding
    • Respiratory: normal or mild tachypnoea, no/mild chest wall retraction, SpO2 >92%, no oxygen requirement or apnoeas
  • Moderate cases:
    • Behaviour: some irritability, may have difficult/reduced feeding
    • Respiratory: tachypnoea, moderate chest wall retraction with nasal flaring, SpO2 90-92%, may require supplemental O2 or have brief apnoeic episodes
  • Severe cases:
    • Behaviour: irritability, lethargy, fatigue, reluctant or unable to feed
    • Respiratory: marked increase respiratory rate, marked work of breathing, SpO2 <90%, hypoxaemia may not be correctable with supplemental O2, frequent or prolonged apnoeas
Investigations
  • Usually a clinical diagnosis (no routine investigations)

  • Chest X-ray (but would want to avoid radiation exposure to children)
  • Nasopharyngeal Aspirate (NPA) for viral PCR
Management
  • Supportive therapy: minimal handling, small frequent feeds for adequate intake
  • Admit children with moderate to severe disease for observation
  • Consider NG at ⅔ maintenance if refusing feeds
  • Supplemental O2 if SpO2 persistently <90%: nasal prongs ± humidified O2 ± Continuous positive airway pressure (CPAP)
  • There is no role for antibiotics/antivirals, salbutamol, steroids or adrenaline